Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26066849 | 1.00 | MDM2 (0.47) | MDM2MDM4TP53HDAC8SIRT2 | |
| SCHEMBL29649526 | 0.93 | MDM2 (0.45) | MDM2MDM4TP53SIRT2SIRT1 | |
| SCHEMBL31681574 | 0.93 | MDM2 (0.45) | MDM2MDM4TP53SIRT2SIRT1 | |
| SCHEMBL12683247 | 0.91 | SSTR3 (0.47) | MDM2HDAC8 | |
| SCHEMBL28615987 | 0.89 | MDM2 (0.39) | MDM2HDAC8 | |
| SCHEMBL15674267 | 0.89 | MDM2 (0.39) | MDM2HDAC8 | |
| SCHEMBL30518584 | 0.88 | PTPN1 (0.45) | MDM2SIRT2SIRT1 | |
| SCHEMBL29414971 | 0.87 | MDM2 (0.59) | MDM2MDM4TP53TLR2 | |
| SCHEMBL13402819 | 0.87 | MDM2 (0.59) | MDM2MDM4TP53TLR2 | |
| SCHEMBL19402725 | 0.87 | MDM2 (0.59) | MDM2MDM4TP53TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270867-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | PINOTBIO, INC. (KR) | 2023-08-31 | — | — | US | disclosed |
| EP-4183418-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | Pinotbio, Inc. (KR) | 2023-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270867-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | SLC46A1, SLC47A1, FOLR1 | MDM2 3932/4885MDM4 3805/4885TP53 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.