Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14381016 | 0.72 | LMNA (0.50) | HTTGAAALDH1A1MAPTKMT2A | |
| SCHEMBL12445601 | 0.67 | GAA (0.42) | HTTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL2096165 | 0.66 | CA12 (0.56) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9320760 | 0.66 | HTT (0.51) | HTTGAAALDH1A1MAPTKMT2A | |
| SCHEMBL2465466 | 0.66 | ALDH1A1 (0.51) | HTTGAAALDH1A1MAPTKMT2A | |
| SCHEMBL28329244 | 0.64 | ALDH1A1 (0.53) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2219799 | 0.64 | CA12 (0.62) | GAAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL27624871 | 0.64 | CA12 (0.52) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11439916 | 0.63 | CA12 (0.56) | ALDH1A1MAPTKMT2AMEN1APLNR | |
| SCHEMBL6706944 | 0.63 | CA12 (0.56) | ALDH1A1MAPTKMT2AMEN1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |