SCHEMBL2219799

SCHEMBL2219799

COc1ccc(F)c(OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CYP1A1 P04798 7/20 0.54
CYP1A2 P05177 7/20 0.54
CYP1B1 Q16678 7/20 0.54
ALDH1A1 P00352 5/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2E1 P05181 1/20 0.48
CYP2C8 P10632 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2A6 P11509 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP4B1 P13584 1/20 0.48
CYP2B6 P20813 1/20 0.48
CYP3A5 P20815 1/20 0.48
CYP2A7 P20853 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7236023 0.92 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL8148997 0.88 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL13058977 0.85 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL22472 0.83 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL1286402 0.83 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL24685887 0.81 NQO1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL12093386 0.81 HTT (0.47) CA12CA1CA2CA7CA9
SCHEMBL19862416 0.81 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL24305884 0.81 CA12 (0.42) CA12CA1CA2CA7CA9
SCHEMBL12093570 0.81 CA12 (0.47) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315579-B1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-01 EP claimed
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
US-10781222-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-09-22 US claimed
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-07-07 US claimed
CN-107709506-B Surface treating agent containing perfluoro (poly) ether group-containing silane compound 大金工业株式会社 2020-06-16 CN claimed
US-20180186820-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2018-07-05 US claimed
EP-3315579-A1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2018-05-02 EP claimed
US-20160340544-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2016-11-24 US claimed
EP-3088487-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2016-11-02 EP claimed
CN-105849222-A Surface treating agent comprising perfluoro (poly) ether group-containing silane compound 大金工业株式会社 2016-08-10 CN claimed
EP-4698520-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF Gandeeva Therapeutics, Inc. (US) 2026-02-25 EP disclosed
US-20260007625-A1 Compounds for the Treatment of Neuromuscular Disorders NMD PHARMA A/S (DK) 2026-01-08 US disclosed
EP-4587418-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-07-23 EP disclosed
WO-2024220708-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF GANDEEVA THERAPEUTICS, INC. (US) 2024-10-24 WO disclosed
EP-3315579-B1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-01 EP disclosed
EP-0802173-A1 Process for producing heterocylic aromatic amine or arylamine Tosoh Corporation (JP) 1997-10-22 EP disclosed
CN-1155279-A Neuroprotective 3-(piperidinyl-1)-chroman-4,7,-diol and 1-(4-hydrophenyl)-2-(piperidinyl-1)-alkane alcohol PFIZER (US) 1997-07-23 CN disclosed
EP-0777652-A1 NEUROPROTECTIVE 3-(PIPERIDINYL-1)-CHROMAN-4,7-DIOL AND 1-(4-HYDROPHENYL)-2-(PIPERIDINYL-1)-ALKANOL DERIVATIVES PFIZER INC. (US) 1997-06-11 EP disclosed
WO-1996037226-A2 COMBINATIONS FOR THE TREATMENT OF PARKINSONISM CONTAINING SELECTIVE NMDA ANTAGONISTS PFIZER INC. (US) 1996-11-28 WO disclosed
WO-1996006081-A1 NEUROPROTECTIVE 3-(PIPERIDINYL-1)-CHROMAN-4,7-DIOL AND 1-(4-HYDROPHENYL)-2-(PIPERIDINYL-1)-ALKANOL DERIVATIVES PFIZER INC. (US) 1996-02-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007625-A1 Compounds for the Treatment of Neuromuscular Disorders RYR1, CACNB1, CACNA1S CA12 2573/4885CA1 1053/4885CA2 262/4885
US-20180186820-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND EPCAM, PFAS, SULT1A1 CA12 602/4885CA1 1148/4885CA2 2120/4885
US-10781222-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound EPCAM, PFAS, SULT1A1 CA12 602/4885CA1 1148/4885CA2 2120/4885
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound FRG1, AFF1, F11 CA12 2012/4885CA1 1187/4885CA2 3504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.