Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PRKX | P51817 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.54 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.54 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451059 | 0.91 | CFD (0.61) | HDAC1MAP4K4PRKCGROCK1PKN2 | |
| SCHEMBL1840592 | 0.85 | APP (0.60) | HDAC1EGFRMAPK1ROCK2RPS6KA5 | |
| SCHEMBL29032712 | 0.83 | HDAC1 (0.69) | HDAC1EGFRMAPK1ROCK2RPS6KA5 | |
| SCHEMBL30450751 | 0.83 | HDAC1 (0.69) | HDAC1EGFRMAPK1ROCK2RPS6KA5 | |
| SCHEMBL29032748 | 0.81 | LMNA (0.52) | HDAC1MAPK1EPHX2NR1H4CA2 | |
| SCHEMBL29032718 | 0.81 | HPGD (0.67) | MEN1KMT2ACYP1A2CYP3A4HPGD | |
| SCHEMBL11615300 | 0.79 | RAB9A (0.74) | CA2FFAR1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11485120 | 0.79 | LMNA (0.54) | MEN1KMT2APOLBMAPTCYP1A2 | |
| SCHEMBL8302813 | 0.78 | SMN1; SMN2 (0.60) | FFAR1MEN1KMT2APOLBMAPT | |
| SCHEMBL30452031 | 0.78 | SMN1; SMN2 (0.57) | MEN1KMT2APOLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |