Sugi Predict

Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL30451260

COc1cc(C#N)c(B(O)O)cc1-c1ccc2c(N)nnc(C)c2c1.O=CO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ XDH P47989 5/20 0.33
▸ S1PR1 P21453 1/20 0.33
▸ KDM4E B2RXH2 4/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ PRMT5 O14744 2/20 0.33
▸ WDR77 Q9BQA1 2/20 0.33
▸ PLAU P00749 1/20 0.33
▸ PGR P06401 1/20 0.33
▸ AR P10275 1/20 0.33
▸ ADORA2A P29274 2/20 0.32
▸ ADORA1 P30542 2/20 0.32
▸ F11 P03951 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ GFER P55789 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ PRKCZ Q05513 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL25266826 1.00 XDH (0.33) XDHS1PR1KDM4EALDH1A1PRMT5
SCHEMBL24252348 0.95 PGR (0.36) XDHS1PR1KDM4EALDH1A1PRMT5
SCHEMBL25211820 0.90 XDH (0.32) XDHS1PR1KDM4EALDH1A1PRMT5
SCHEMBL26771301 0.89 PGR (0.34) XDHS1PR1KDM4EALDH1A1PRMT5
Formic Acid SCHEMBL25259596 0.87 DHFR (0.33) —
Formic Acid SCHEMBL30453086 0.87 DHFR (0.33) —
Formic Acid SCHEMBL30451510 0.83 SOS1 (0.32) ALDH1A1
Formic Acid SCHEMBL25266916 0.83 SOS1 (0.32) ALDH1A1
SCHEMBL24252646 0.81 DHFR (0.36) ALDH1A1PLAUMEN1KMT2ATDP1
Formic Acid SCHEMBL25242412 0.81 DHFR (0.37) PLAUF11MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 — — US disclosed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 — — US disclosed
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON, INC. 2024-04-04 — — US disclosed
US-11814404-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2023-11-14 — — US disclosed
CN-116947903-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-10-27 — — CN disclosed
CN-116261564-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-06-13 — — CN disclosed
EP-4185592-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF Annexon, Inc. (US) 2023-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFB, CFH, C9 XDH 228/4885S1PR1 372/4885KDM4E 3923/4885
US-11814404-B2 Inhibitors of complement factors and uses thereof CFB, CFH, C9 XDH 228/4885S1PR1 372/4885KDM4E 3923/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH XDH 222/4885S1PR1 2042/4885KDM4E 2913/4885
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFH, CFB, C5 XDH 65/4885S1PR1 1076/4885KDM4E 4178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.