Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | FABP6 | P51161 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032791 | 0.84 | USP30 (0.58) | SMN1; SMN2MAPK1ABL1FABP6EGLN1 | |
| SCHEMBL30452219 | 0.84 | USP30 (0.58) | SMN1; SMN2MAPK1ABL1FABP6EGLN1 | |
| SCHEMBL29032775 | 0.83 | CFD (0.59) | SMN1; SMN2ABL1FABP6EGLN1CYP2D6 | |
| SCHEMBL30452215 | 0.83 | CFD (0.59) | SMN1; SMN2ABL1FABP6EGLN1CYP2D6 | |
| SCHEMBL29032785 | 0.80 | CFD (0.53) | SMN1; SMN2ABL1FABP6EGLN1CYP2D6 | |
| SCHEMBL4239965 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL29032725 | 0.74 | MMP2 (0.52) | SMN1; SMN2HTTABL1KDM4E | |
| SCHEMBL30450735 | 0.74 | MMP2 (0.52) | SMN1; SMN2HTTABL1KDM4E | |
| SCHEMBL24137465 | 0.71 | RAB9A (0.46) | SMN1; SMN2KMT2AMEN1MAPK1HTT | |
| SCHEMBL29386710 | 0.71 | PLAU (0.54) | SMN1; SMN2HTTABL1FABP6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |