Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729579 | 1.00 | NPSR1 (0.50) | NPSR1L3MBTL1MALT1POLBHPGD | |
| SCHEMBL21437557 | 0.85 | RAB9A (0.48) | POLBHPGDWDR5RAB9AKMT2A | |
| SCHEMBL12845660 | 0.84 | F2 (0.44) | L3MBTL1HPGDWDR5RAB9AKMT2A | |
| SCHEMBL15543495 | 0.83 | NPSR1 (0.50) | NPSR1L3MBTL1HPGDSETDB1RAB9A | |
| SCHEMBL30001281 | 0.83 | NPSR1 (0.50) | NPSR1L3MBTL1HPGDSETDB1RAB9A | |
| SCHEMBL26693753 | 0.82 | SMN1; SMN2 (0.47) | POLBHPGDWDR5RAB9AKMT2A | |
| SCHEMBL27313119 | 0.82 | BACE1 (0.36) | NPSR1L3MBTL1MALT1POLBHPGD | |
| SCHEMBL27170354 | 0.81 | WDR5 (0.45) | L3MBTL1HPGDWDR5RAB9AKMT2A | |
| SCHEMBL5861280 | 0.81 | HTT (0.47) | L3MBTL1POLBHPGDKMT2AMEN1 | |
| SCHEMBL17801961 | 0.81 | NPSR1 (0.51) | NPSR1L3MBTL1HPGDSETDB1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |