Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845660 | 0.88 | F2 (0.44) | HTTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL5729579 | 0.81 | NPSR1 (0.50) | HPGDALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30451523 | 0.81 | NPSR1 (0.50) | HPGDALDH1A1MEN1KMT2APOLB | |
| SCHEMBL12845344 | 0.81 | ALOX15 (0.69) | HTTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL21437557 | 0.80 | RAB9A (0.48) | HPGDMEN1KMT2APOLBF2 | |
| SCHEMBL12845330 | 0.77 | POLB (0.68) | HPGDALDH1A1MEN1KMT2APOLB | |
| SCHEMBL26693753 | 0.77 | SMN1; SMN2 (0.47) | HPGDALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1690435 | 0.77 | HPGD (0.68) | HPGDALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27170354 | 0.77 | WDR5 (0.45) | HTTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL11286425 | 0.76 | GSK3A (0.54) | HPGDALDH1A1MEN1KMT2AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060752-B2 | Synthesis and use of nitrophenol resins | NEW YORK UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |
| US-20040087726-A1 | Synthesis and use of nitrophenol resins | NEW YORK UNIVERSITY | 2004-05-06 | — | — | US | disclosed |