Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26772062 | 1.00 | APLNR (0.33) | APLNRNT5EHSD11B1PDE2AKDM4E | |
| SCHEMBL21356098 | 0.80 | — | — | |
| SCHEMBL6299967 | 0.74 | PYCR1 (0.39) | APLNRKDM4EPOLBMAPTHTT | |
| SCHEMBL19812843 | 0.74 | CA1 (0.36) | HSD11B1 | |
| SCHEMBL12002574 | 0.72 | DUT (0.33) | — | |
| SCHEMBL13936226 | 0.71 | GBA1 (0.32) | — | |
| SCHEMBL29268112 | 0.71 | HSD11B1 (0.41) | NT5EHSD11B1PDE2AKDM4EPOLB | |
| SCHEMBL16744595 | 0.71 | — | — | |
| SCHEMBL195484 | 0.71 | SLC6A4 (0.36) | APLNRHTT | |
| SCHEMBL24252824 | 0.71 | NT5E (0.37) | NT5EHSD11B1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |