Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.41 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27844899 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL4284692 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL13153171 | 0.81 | KDM4E (0.40) | ALDH1A1MEN1KMT2ATP53BLM | |
| SCHEMBL112942 | 0.80 | MAP2K3 (0.46) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL28235893 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL6274465 | 0.78 | MEN1 (0.40) | ALDH1A1MEN1KMT2ATP53BLM | |
| SCHEMBL3205661 | 0.77 | IGFBP3 (0.49) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL5500061 | 0.76 | MAP2K3 (0.57) | ALDH1A1MEN1KMT2ATP53KDM4E | |
| SCHEMBL5100092 | 0.76 | LCK (0.47) | ALDH1A1MEN1KMT2ATP53KDM4E | |
| SCHEMBL28916905 | 0.76 | SSTR4 (0.45) | ALDH1A1KDM4ELMNAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2023-02-09 | — | — | US | disclosed |
| CN-115038698-A | Thienyl oxazolones and analogs | 拜耳公司 | 2022-09-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | HAVCR2, HMBS, AHCY | ALDH1A1 2620/4885MEN1 1955/4885KMT2A 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.