Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252276 | 1.00 | ABL1 (0.33) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL26771101 | 0.93 | ABL1 (0.32) | ABL1PRMT5WDR77 | |
| SCHEMBL30451875 | 0.84 | ABL1 (0.33) | ABL1PRMT5WDR77ESR1ESR2 | |
| SCHEMBL24252366 | 0.84 | ABL1 (0.33) | ABL1PRMT5WDR77ESR1ESR2 | |
| SCHEMBL24252348 | 0.82 | PGR (0.36) | PRMT5WDR77 | |
| SCHEMBL26771076 | 0.81 | ABL1 (0.33) | ABL1PRMT5WDR77 | |
| SCHEMBL24252646 | 0.80 | DHFR (0.36) | — | |
| SCHEMBL26771301 | 0.78 | PGR (0.34) | PRMT5WDR77 | |
| Formic Acid SCHEMBL30451260 | 0.78 | XDH (0.33) | PRMT5WDR77 | |
| Formic Acid SCHEMBL25266826 | 0.78 | XDH (0.33) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |