Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254423 | 0.80 | KDM4E (0.41) | KDM4EGPR3GABRA1GABRG2GABRB3 | |
| SCHEMBL29254513 | 0.79 | ALDH1A1 (0.50) | KDM4EGAAMAP4K4CSF1RFGFR1 | |
| SCHEMBL4548298 | 0.76 | GABRA1 (0.38) | KDM4EGPR3GABRA1GABRG2GABRB3 | |
| SCHEMBL4728664 | 0.75 | DYRK1A (0.46) | CDK5CLK4DYRK1BGABRA1GABRG2 | |
| SCHEMBL1897984 | 0.73 | KMT2A (0.43) | KDM4EPDPK1CYP3A4GAACDK5 | |
| SCHEMBL19020845 | 0.70 | GPR3 (0.68) | KDM4EPDPK1CYP3A4PI4KAPI4K2B | |
| SCHEMBL29116723 | 0.69 | CHEK1 (0.53) | KDM4EPDPK1CYP3A4GAAMAP4K4 | |
| SCHEMBL18264145 | 0.69 | CHEK1 (0.49) | KDM4EPDPK1CYP3A4GAAMAP4K4 | |
| SCHEMBL842044 | 0.69 | QTRT1 (0.51) | KDM4EGAAPI4KAPI4K2BPI4K2A | |
| SCHEMBL23145214 | 0.68 | GPR3 (0.44) | KDM4EPDPK1GPR3GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113038949-B | Neutrophil inflammation inhibitor and application thereof | 长庚学校长庚科技大学 | 2023-07-14 | — | — | CN | disclosed |