Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.51 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488836 | 1.00 | MET (0.51) | METMAP4K3CHEK2ALKJAK2 | |
| SCHEMBL30452704 | 0.95 | MET (0.45) | METMAP4K3CHEK2 | |
| SCHEMBL488978 | 0.95 | MET (0.45) | METMAP4K3CHEK2 | |
| SCHEMBL30452428 | 0.85 | MET (0.63) | METALKJAK2 | |
| SCHEMBL487817 | 0.85 | MET (0.63) | METALKJAK2 | |
| SCHEMBL30453380 | 0.84 | MET (0.55) | METMAP4K3CHEK2 | |
| SCHEMBL488697 | 0.84 | MET (0.55) | METMAP4K3CHEK2 | |
| SCHEMBL488395 | 0.82 | CNR1 (0.49) | METMAP4K3ALK | |
| SCHEMBL30453036 | 0.82 | CNR1 (0.49) | METMAP4K3ALK | |
| SCHEMBL488027 | 0.82 | MET (0.38) | METALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |