Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257722 | 0.85 | HPGD (0.48) | ALDH1A1SMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL24257699 | 0.76 | HPGD (0.44) | ALDH1A1HPGDL3MBTL1RAB9ANPC1 | |
| SCHEMBL30546822 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDKDM4EPOLB | |
| SCHEMBL30452553 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDKDM4EPOLB | |
| SCHEMBL24257545 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDKDM4EPOLB | |
| SCHEMBL24257727 | 0.74 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL24257534 | 0.74 | CASP1 (0.49) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL30453195 | 0.74 | CASP1 (0.49) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL24257697 | 0.74 | EGLN1 (0.50) | RAB9AEGLN1GAA | |
| SCHEMBL24257576 | 0.74 | TRPM8 (0.41) | ALDH1A1SMN1; SMN2HPGDL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |