SCHEMBL30453316

SCHEMBL30453316

C[Si](C)=[Hf](C1C=CC=C1)C1c2ccc(C(C)(C)C)cc2-c2cc(C(C)(C)C)ccc21

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PLA2G1B P04054 1/20 0.32
NFKB1 P19838 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
KIF11 P52732 8/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30108358 0.88 KIF11 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30785883 0.86 NPC1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30452158 0.80 HTR2C (0.30)
SCHEMBL30451507 0.77 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30785893 0.75 NPC1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL21270141 0.74 GPR3 (0.34)
SCHEMBL30785862 0.72 NPC1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL28498746 0.72 ALDH1A1 (0.40) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL21270132 0.71 KCNK9 (0.35) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30452142 0.71 ALDH1A1 (0.31) NPC1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101156-A1 POLYOLEFIN COMPOSITIONS FEATURING IN SITU BLENDING OF AN OIL EXTENSION EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2025-03-27 US disclosed
US-12202920-B2 Olefin polymerization processes featuring in situ blending of an oil extension ExxonMobil Engineering & Technology Company (US) 2025-01-21 US disclosed
US-12006423-B2 Methods of making polymer compositions with enhanced elasticity by employing VTP and HMP catalyst systems in parallel processes ExxonMobil Engineering & Technology Company (US) 2024-06-11 US disclosed
EP-3841168-B1 METHODS OF MAKING POLYMER COMPOSITIONS WITH ENHANCED ELASTICITY BY EMPLOYING VTP AND HMP CATALYST SYSTEMS IN PARALLEL PROCESSES EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-01-17 EP disclosed
US-11708434-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-07-25 US disclosed