SCHEMBL30452142

SCHEMBL30452142

Cc1ccc2c(c1)C([Hf](C1C=CC=C1)=[Si](C)C)c1cc(C)ccc1-2

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
KMT2A Q03164 1/20 0.31
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30452158 0.87 HTR2C (0.30) HTR2C
SCHEMBL30785887 0.85
SCHEMBL30108358 0.80 KIF11 (0.33) ALDH1A1NPC1
SCHEMBL21270141 0.78 GPR3 (0.34)
SCHEMBL30785882 0.73
SCHEMBL30453316 0.71 NPC1 (0.32) ALDH1A1CYP1A2NPC1
SCHEMBL6903253 0.69 MAOA (0.35) ALDH1A1CYP1A2HPGDHSD17B10KDM4E
SCHEMBL29907875 0.69 CES2 (0.33) ALDH1A1CYP1A2HPGDHSD17B10KDM4E
SCHEMBL30785893 0.67 NPC1 (0.32) ALDH1A1NPC1
SCHEMBL21633426 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101156-A1 POLYOLEFIN COMPOSITIONS FEATURING IN SITU BLENDING OF AN OIL EXTENSION EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2025-03-27 US disclosed
US-12202920-B2 Olefin polymerization processes featuring in situ blending of an oil extension ExxonMobil Engineering & Technology Company (US) 2025-01-21 US disclosed
US-12006423-B2 Methods of making polymer compositions with enhanced elasticity by employing VTP and HMP catalyst systems in parallel processes ExxonMobil Engineering & Technology Company (US) 2024-06-11 US disclosed
EP-3841168-B1 METHODS OF MAKING POLYMER COMPOSITIONS WITH ENHANCED ELASTICITY BY EMPLOYING VTP AND HMP CATALYST SYSTEMS IN PARALLEL PROCESSES EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-01-17 EP disclosed
US-11708434-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-07-25 US disclosed