Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 7/20 | 0.69 |
| ▸ | MET | P08581 | 3/20 | 0.62 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488215 | 1.00 | MAP4K4 (0.69) | MAP4K4METMAP4K3EPHX2RXRA | |
| SCHEMBL30454707 | 0.88 | MAP4K3 (0.58) | MAP4K4METMAP4K3MAOB | |
| SCHEMBL487859 | 0.88 | MAP4K3 (0.58) | MAP4K4METMAP4K3MAOB | |
| SCHEMBL30454601 | 0.85 | MAP4K4 (0.62) | MAP4K4MET | |
| SCHEMBL487894 | 0.85 | MAP4K4 (0.62) | MAP4K4MET | |
| SCHEMBL30453136 | 0.84 | MAP4K3 (0.55) | MAP4K4METMAP4K3MAOB | |
| SCHEMBL487832 | 0.84 | MAP4K4 (0.73) | MAP4K4METMAP4K3 | |
| SCHEMBL30454971 | 0.84 | MAP4K4 (0.73) | MAP4K4METMAP4K3 | |
| SCHEMBL488532 | 0.83 | MET (0.65) | MAP4K4METMAP4K3MAOBMAOA | |
| SCHEMBL30453327 | 0.83 | MET (0.65) | MAP4K4METMAP4K3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |