Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 3/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | USP7 | Q93009 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487859 | 1.00 | MAP4K3 (0.58) | MAP4K3METMAP4K4USP7FYN | |
| SCHEMBL30453475 | 0.88 | MAP4K4 (0.69) | MAP4K3METMAP4K4MAOB | |
| SCHEMBL488215 | 0.88 | MAP4K4 (0.69) | MAP4K3METMAP4K4MAOB | |
| SCHEMBL30453136 | 0.86 | MAP4K3 (0.55) | MAP4K3METMAP4K4IDO1MAOB | |
| SCHEMBL27630255 | 0.86 | MAP4K3 (0.55) | MAP4K3METMAP4K4FYNIDO1 | |
| SCHEMBL27629997 | 0.82 | MET (0.61) | MAP4K3METMAP4K4 | |
| SCHEMBL30452824 | 0.81 | MET (0.75) | MAP4K3METMAP4K4USP7FYN | |
| SCHEMBL487657 | 0.81 | MET (0.75) | MAP4K3METMAP4K4USP7FYN | |
| SCHEMBL27630242 | 0.81 | MET (0.75) | MAP4K3METMAP4K4USP7FYN | |
| SCHEMBL488094 | 0.81 | MAP4K3 (0.52) | MAP4K3METMAP4K4FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |