Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 4/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629997 | 0.87 | MET (0.61) | MAP4K3METMAP4K4NEK2PTPN1 | |
| SCHEMBL487859 | 0.86 | MAP4K3 (0.58) | MAP4K3METMAP4K4PLK1IDO1 | |
| SCHEMBL30454707 | 0.86 | MAP4K3 (0.58) | MAP4K3METMAP4K4PLK1IDO1 | |
| SCHEMBL488215 | 0.84 | MAP4K4 (0.69) | MAP4K3METMAP4K4MAOB | |
| SCHEMBL30453475 | 0.84 | MAP4K4 (0.69) | MAP4K3METMAP4K4MAOB | |
| SCHEMBL27630255 | 0.83 | MAP4K3 (0.55) | MAP4K3METMAP4K4PLK1IDO1 | |
| SCHEMBL488094 | 0.78 | MAP4K3 (0.52) | MAP4K3METMAP4K4 | |
| SCHEMBL27630123 | 0.77 | MET (0.51) | MAP4K3METMAP4K4IDO1 | |
| SCHEMBL27650234 | 0.77 | MET (0.51) | MAP4K3METMAP4K4 | |
| SCHEMBL488609 | 0.77 | MAP4K3 (0.52) | MAP4K3METMAP4K4PLK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |