Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.68 |
| ▸ | PARP1 | P09874 | 6/20 | 0.68 |
| ▸ | F7 | P08709 | 1/20 | 0.68 |
| ▸ | F3 | P13726 | 1/20 | 0.68 |
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | MST1R | Q04912 | 1/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.50 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391640 | 1.00 | PARP10 (0.68) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL793493 | 0.82 | PARP10 (1.00) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL29676942 | 0.82 | PARP10 (1.00) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL797294 | 0.77 | PARP10 (0.76) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL8151102 | 0.76 | PARP10 (0.70) | PARP10PARP1PARP11NTRK1FLT3 | |
| SCHEMBL1315035 | 0.76 | PARP10 (0.74) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL19088736 | 0.75 | ASIC3 (0.60) | CD274 | |
| SCHEMBL18112980 | 0.74 | MAPK1 (0.56) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL8155836 | 0.74 | PARP10 (0.76) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL8155829 | 0.73 | PARP11 (0.68) | PARP10PARP1PARP11METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |