Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 5/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25354604 | 1.00 | KCNH2 (0.46) | KCNH2TMEM97SIGMAR1SMN1; SMN2ENPP2 | |
| SCHEMBL24254583 | 0.80 | SMN1; SMN2 (0.45) | KCNH2TMEM97SIGMAR1SMN1; SMN2PTGS2 | |
| SCHEMBL4425900 | 0.80 | LMNA (0.54) | SMN1; SMN2RORCPTGDR2CYP3A4CACNA1B | |
| SCHEMBL18230961 | 0.78 | FFAR4 (0.43) | KCNH2TMEM97SIGMAR1SMN1; SMN2PTGS2 | |
| SCHEMBL28826127 | 0.77 | SMN1; SMN2 (0.40) | KCNH2TMEM97SIGMAR1SMN1; SMN2RORC | |
| SCHEMBL23143746 | 0.77 | G6PD (0.49) | KCNH2TMEM97SIGMAR1SMN1; SMN2PTGS2 | |
| SCHEMBL18230946 | 0.77 | MAPT (0.44) | KCNH2TMEM97SIGMAR1SMN1; SMN2PTGS2 | |
| SCHEMBL23155765 | 0.74 | LRRK2 (0.46) | KCNH2TMEM97SIGMAR1SMN1; SMN2PTGS2 | |
| SCHEMBL3721044 | 0.73 | SLC6A4 (0.40) | KCNH2TMEM97SIGMAR1SMN1; SMN2PTGS2 | |
| SCHEMBL26418355 | 0.73 | CNR2 (0.43) | KCNH2TMEM97SIGMAR1SMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |