Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273592 | 0.74 | IDO1 (0.53) | IDO1PTPN1KDM4EALDH1A1HPGD | |
| SCHEMBL278699 | 0.62 | NR1H4 (0.58) | IDO1PTPN1KDM4EALDH1A1HPGD | |
| SCHEMBL273038 | 0.62 | NR1H4 (0.58) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL274161 | 0.60 | NR1H4 (0.59) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL273348 | 0.60 | KDM4E (0.51) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL18712857 | 0.58 | IDO1 (0.46) | IDO1PTPN1KDM4EALDH1A1HPGD | |
| SCHEMBL25358406 | 0.58 | HTR2C (0.43) | KDM4EHSD17B10MAPK1PARP1CYP1A2 | |
| SCHEMBL30455186 | 0.58 | HTR2C (0.43) | KDM4EHSD17B10MAPK1PARP1CYP1A2 | |
| SCHEMBL70573 | 0.57 | CA12 (0.60) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL27647692 | 0.56 | CHRM3 (0.44) | PTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145638-A1 | Serotonin Receptor Agonists and Methods of Making and Using the Same | KULEON LLC (US) | 2025-05-08 | — | — | US | disclosed |
| EP-4452986-A1 | SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME | Kuleon LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023122135-A1 | SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145638-A1 | Serotonin Receptor Agonists and Methods of Making and Using the Same | HTR1A, HTR3A, HTR5A | IDO1 634/4885PTPN1 3519/4885KDM4E 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.