Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455036 | 0.92 | KCNH2 (0.43) | KCNH2IKBKBPDE10AKDM4ENPC1 | |
| Formic Acid SCHEMBL30454732 | 0.78 | DYRK1A (0.46) | KCNH2PDE10ALMNAHSP90AA1TDO2 | |
| Formic Acid SCHEMBL30455244 | 0.74 | SOS1 (0.43) | KCNH2 | |
| SCHEMBL2261387 | 0.72 | KCNH2 (0.50) | KCNH2KDM4ENPC1L3MBTL1SMN1; SMN2 | |
| Formic Acid SCHEMBL30454871 | 0.70 | DCPS (0.52) | KCNH2KDM4ENPC1ALOX15MAPK1 | |
| SCHEMBL16370045 | 0.70 | KDM4E (0.50) | PDE10AKDM4ENPC1L3MBTL1ALOX15 | |
| SCHEMBL5205380 | 0.69 | KDM4E (0.47) | KDM4ENPC1L3MBTL1ALOX15MAPK1 | |
| SCHEMBL16876610 | 0.68 | TDO2 (0.47) | IKBKBPDE10AKDM4ENPC1L3MBTL1 | |
| Dipyridyl SCHEMBL27994607 | 0.67 | KDM4E (0.70) | KDM4ENPC1L3MBTL1ALOX15MAPK1 | |
| SCHEMBL6422359 | 0.67 | DCPS (0.45) | KCNH2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |