Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30454802 | 0.92 | KCNH2 (0.39) | KCNH2KDM4EL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL2261387 | 0.78 | KCNH2 (0.50) | KCNH2KDM4EL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL16370045 | 0.76 | KDM4E (0.50) | KDM4EL3MBTL1SMN1; SMN2NPC1ALOX15 | |
| SCHEMBL5205380 | 0.75 | KDM4E (0.47) | KDM4EL3MBTL1SMN1; SMN2NPC1ALOX15 | |
| SCHEMBL16876610 | 0.73 | TDO2 (0.47) | KDM4EL3MBTL1SMN1; SMN2NPC1ALOX15 | |
| SCHEMBL6422359 | 0.72 | DCPS (0.45) | KCNH2DCPSAKT1ALDH1A1 | |
| SCHEMBL9260727 | 0.72 | ACHE (0.47) | KCNH2KDM4ESMN1; SMN2CYP1A2POLB | |
| SCHEMBL26260016 | 0.71 | KDM4E (0.58) | KDM4EL3MBTL1SMN1; SMN2NPC1ALOX15 | |
| SCHEMBL28963427 | 0.70 | KDM4E (0.52) | KDM4EL3MBTL1SMN1; SMN2NPC1ALOX15 | |
| SCHEMBL22930330 | 0.70 | PIK3CD (0.51) | KDM4ESMN1; SMN2NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |