SCHEMBL30455653

SCHEMBL30455653

O=CCC(=O)N1CCNCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA9 Q16790 1/20 0.45
CHKA P35790 1/20 0.43
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA4 P43681 1/20 0.42
CHRNB3 Q05901 1/20 0.42
CHRNA6 Q15825 1/20 0.42
TPSAB1 Q15661 1/20 0.41
TPSD1 Q9BZJ3 1/20 0.41
TPSG1 Q9NRR2 1/20 0.41
SIGMAR1 Q99720 1/20 0.37
HSD11B1 P28845 1/20 0.36
POLB P06746 2/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186109 0.81 CA2 (0.43) CA2CA12CA1CA9CHKA
SCHEMBL3898267 0.81 CA2 (0.43) CA2CA12CA1CA9CHKA
SCHEMBL6203722 0.79 ATM (0.52) KMT2AGAA
SCHEMBL3082371 0.79 ATM (0.52) KMT2AGAA
SCHEMBL12443868 0.79 DDB1 (0.44) CA2CA12CA1CA9CHKA
SCHEMBL27396631 0.77 ATM (0.50) KMT2AGAA
SCHEMBL6778757 0.76 CA2 (0.39) CA2CA12CA1CA9CHKA
SCHEMBL22111991 0.76 ATM (0.45) CA2CA12CA1CA9CHKA
SCHEMBL4184360 0.76 ALDH1A1 (0.38) HSD11B1POLBKMT2AGAA
SCHEMBL28191935 0.75 CA2 (0.46) CA2CA12CA1CA9CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023121378-A1 (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-06-29 WO disclosed