Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203722 | 0.81 | ATM (0.52) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL3082371 | 0.81 | ATM (0.52) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL3949996 | 0.80 | CYP1A2 (0.48) | KMT2ATDP1MAPTSMN1; SMN2POLB | |
| SCHEMBL8185942 | 0.80 | CYP1A2 (0.48) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL27396631 | 0.79 | ATM (0.50) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL30455653 | 0.76 | CA2 (0.45) | KMT2AGAAPOLBHSD11B1 | |
| SCHEMBL3582413 | 0.76 | L3MBTL1 (0.55) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL3955618 | 0.75 | TP53 (0.53) | ALDH1A1LMNAHPGDTDP1TSHR | |
| SCHEMBL16904 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL9079929 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029375-A1 | NOVEL INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | LEAD THERAPEUTICS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |