Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 18/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 18/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.67 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15794608 | 1.00 | OPRM1 (1.00) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL550284 | 0.90 | OPRL1 (0.84) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL28667548 | 0.89 | OPRM1 (0.80) | OPRM1OPRL1OPRK1 | |
| SCHEMBL3872453 | 0.87 | OPRM1 (1.00) | OPRM1OPRL1OPRK1OPRD1OGFRL1 | |
| SCHEMBL10063412 | 0.87 | OPRL1 (0.77) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL1857323 | 0.87 | OPRM1 (0.85) | OPRM1OPRL1OPRK1 | |
| SCHEMBL9837438 | 0.86 | OPRM1 (0.75) | OPRM1OPRL1OPRK1 | |
| SCHEMBL27604615 | 0.85 | OPRM1 (1.00) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL1943948 | 0.85 | OPRM1 (0.74) | OPRM1OPRL1OPRK1 | |
| SCHEMBL15794617 | 0.83 | OPRM1 (1.00) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085826-A1 | ACTIVATION OF ORL1: A NOVEL THERAPY TO PREVENT HEART FAILURE PROGRESSION | BAYLOR COLLEGE OF MEDICINE (US) | 2025-04-24 | — | — | WO | claimed |
| US-20260060822-A1 | BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2026-03-05 | — | — | US | disclosed |
| US-20250366979-A1 | DEVICES AND METHODS OF MAKING AND USE THEREOF | METHODIST HOSPITAL (US) | 2025-12-04 | — | — | US | disclosed |
| US-20250366978-A1 | DEVICES AND METHODS OF MAKING AND USE THEREOF | METHODIST HOSPITAL (US) | 2025-12-04 | — | — | US | disclosed |
| US-20250251323-A1 | COLLECTION PROBE AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE | 2025-08-07 | — | — | US | disclosed |
| WO-2025085826-A1 | ACTIVATION OF ORL1: A NOVEL THERAPY TO PREVENT HEART FAILURE PROGRESSION | BAYLOR COLLEGE OF MEDICINE (US) | 2025-04-24 | — | — | WO | disclosed |
| EP-4536138-A1 | DEVICES AND METHODS OF MAKING AND USE THEREOF | The Methodist Hospital (US) | 2025-04-16 | — | — | EP | disclosed |
| EP-4536139-A1 | DEVICES AND METHODS OF MAKING AND USE THEREOF | The Methodist Hospital (US) | 2025-04-16 | — | — | EP | disclosed |
| EP-4507825-A1 | COLLECTION PROBE AND METHODS OF USE THEREOF | Board of Regents, The University of Texas System (US) | 2025-02-19 | — | — | EP | disclosed |
| WO-2024211329-A2 | DEVICES AND METHODS OF MAKING AND USE THEREOF | THE METHODIST HOSPITAL (US) | 2024-10-10 | — | — | WO | disclosed |
| WO-2024044315-A1 | BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2023244797-A1 | DEVICES AND METHODS OF MAKING AND USE THEREOF | THE METHODIST HOSPITAL SYSTEM (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023244821-A1 | DEVICES AND METHODS OF MAKING AND USE THEREOF | THE METHODIST HOSPITAL SYSTEM (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023200850-A1 | COLLECTION PROBE AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-19 | — | — | WO | disclosed |
| US-20230181569-A1 | COMPOSITIONS AND METHODS TO TREAT POLYCYSTIC KIDNEY DISEASE | UNIV LOUISIANA STATE (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060822-A1 | BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF | PFKP, PBK, MYLK | OPRM1 4810/4885OPRL1 4863/4885OPRK1 2862/4885 |
| US-20230181569-A1 | COMPOSITIONS AND METHODS TO TREAT POLYCYSTIC KIDNEY DISEASE | OPRK1, OPRL1, AVPR1A | OPRM1 8/4885OPRL1 2/4885OPRK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.