Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 7/20 | 0.51 |
| ▸ | CDK2 | P24941 | 7/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15377583 | 0.81 | FFAR2 (0.51) | CCNE1CDK2CDK5FFAR2HCAR2 | |
| SCHEMBL186141 | 0.79 | HCAR2 (0.53) | CCNE1CDK2CDK5CSNK2A2CSNK2A1 | |
| SCHEMBL6883628 | 0.76 | FFAR2 (0.49) | CCNE1CDK2CDK5FFAR2HCAR2 | |
| SCHEMBL4252915 | 0.76 | HCAR2 (0.46) | CCNE1CDK2CDK5FFAR2HCAR2 | |
| SCHEMBL20819347 | 0.75 | CCNE1 (0.64) | CCNE1CDK2CDK5FFAR2HCAR2 | |
| SCHEMBL22750823 | 0.74 | HCAR2 (0.52) | CCNE1CDK2CDK5FFAR2HCAR2 | |
| SCHEMBL4256153 | 0.74 | RAB9A (0.65) | CCNE1CDK2CDK5FFAR2HCAR2 | |
| SCHEMBL16113553 | 0.74 | HCAR2 (0.52) | CCNE1CDK2CDK5FFAR2HCAR2 | |
| SCHEMBL12272298 | 0.73 | CCNE1 (0.62) | CCNE1CDK2CDK5SMN1; SMN2CCNT1 | |
| SCHEMBL2664534 | 0.73 | KDR (0.68) | CCNE1CDK2CDK5CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129366-A1 | THIAZOLE INHIBITORS OF CYCLOOXYGENASE | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129366-A1 | THIAZOLE INHIBITORS OF CYCLOOXYGENASE | PTGES2, PTGES, PTGES3 | CCNE1 3687/4885CDK2 429/4885CDK5 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.