Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962927 | 0.81 | PLAU (0.50) | PLAUCYP2C9CYP2A6TSHRCYP3A4 | |
| SCHEMBL93291 | 0.77 | CYP3A4 (0.68) | PLAUCYP2C9CYP2A6TSHRCYP3A4 | |
| SCHEMBL19129733 | 0.77 | PLAU (0.47) | PLAUCYP2C9CYP2A6TSHRCYP3A4 | |
| SCHEMBL1436221 | 0.77 | P2RY6 (0.68) | PLAUCYP2C9CYP2A6TSHRCYP3A4 | |
| SCHEMBL27845847 | 0.77 | PLAU (0.47) | PLAUCYP2C9CYP2A6TSHRCYP3A4 | |
| SCHEMBL8740945 | 0.73 | ACHE (0.42) | PLAUCYP2C9CYP2A6TSHRGRIN2D | |
| SCHEMBL29200026 | 0.73 | CYP3A4 (0.43) | CYP2C9TSHRCYP3A4P2RY6TP53 | |
| SCHEMBL6414291 | 0.72 | P2RY6 (0.61) | PLAUCYP2C9CYP2A6TSHRCYP3A4 | |
| SCHEMBL24212689 | 0.72 | PLAU (0.56) | PLAUCYP2C9CYP2A6TSHRGRIN2D | |
| SCHEMBL13638200 | 0.72 | PLAU (0.56) | PLAUCYP2C9CYP2A6TSHRGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552779-B2 | 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases | DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2026-02-17 | — | — | US | disclosed |
| US-20240358679-A1 | PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES | INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (KR) | 2024-10-31 | — | — | US | disclosed |
| US-20230286956-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | KNU- INDUSTRY COOPERATION FOUNDATION (KR) | 2023-09-14 | — | — | US | disclosed |
| WO-2023132681-A1 | PHARMACEUTICAL COMPOSITION AND FOOD COMPOSITION COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND DERIVATIVE THEREOF FOR PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASE | 덕성여자대학교 산학협력단 | 2023-07-13 | — | — | WO | disclosed |
| EP-4183776-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | Duksung Women's University Industry-Academic Cooperation Foundation (KR) | 2023-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552779-B2 | 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases | SNCA, HTT, PSEN1 | PLAU 4794/4885CYP2C9 2547/4885CYP2A6 1519/4885 |
| US-20230286956-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | PSEN2, PARK7, SNCA | PLAU 4162/4885CYP2C9 2813/4885CYP2A6 1875/4885 |
| US-20240358679-A1 | PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES | GPX4, GPX1, SELENOI | PLAU 2704/4885CYP2C9 482/4885CYP2A6 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.