Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159755 | 0.78 | ACHE (0.47) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL7620354 | 0.76 | ACHE (0.44) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL10895667 | 0.74 | HTR3E (0.46) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL93286 | 0.74 | CYP3A4 (0.56) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL1011250 | 0.74 | ACHE (0.42) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL9887642 | 0.74 | ACHE (0.42) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL332260 | 0.74 | MIF (0.56) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL10898456 | 0.72 | ALDH1A1 (0.44) | ACHETDP1HTR3EHTR3BHTR3A | |
| SCHEMBL15086596 | 0.72 | ACHE (0.40) | ACHETDP1HTR3EHTR3BHTR3A | |
| Hydrogen Sulfide SCHEMBL27351182 | 0.72 | CYP3A4 (0.54) | ACHETDP1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552779-B2 | 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases | DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2026-02-17 | — | — | US | disclosed |
| US-20240358679-A1 | PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES | INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (KR) | 2024-10-31 | — | — | US | disclosed |
| US-20230286956-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | KNU- INDUSTRY COOPERATION FOUNDATION (KR) | 2023-09-14 | — | — | US | disclosed |
| WO-2023132681-A1 | PHARMACEUTICAL COMPOSITION AND FOOD COMPOSITION COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND DERIVATIVE THEREOF FOR PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASE | 덕성여자대학교 산학협력단 | 2023-07-13 | — | — | WO | disclosed |
| EP-4183776-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | Duksung Women's University Industry-Academic Cooperation Foundation (KR) | 2023-05-24 | — | — | EP | disclosed |
| US-5654134-A | CHEMICAL RIPENING INPRESENCE OF A LABILE TELLURIUM OR SELENIUM SENSITIZER | FUJI PHOTO FILM CO., LTD. (JP) | 1997-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552779-B2 | 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases | SNCA, HTT, PSEN1 | ACHE 182/4885TDP1 478/4885HTR3E 3168/4885 |
| US-20230286956-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | PSEN2, PARK7, SNCA | ACHE 90/4885TDP1 579/4885HTR3E 3859/4885 |
| US-20240358679-A1 | PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES | GPX4, GPX1, SELENOI | ACHE 2226/4885TDP1 4226/4885HTR3E 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.