Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718074 | 1.00 | MEN1 (0.54) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL4362709 | 0.87 | LMNA (0.56) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL1431527 | 0.84 | LMNA (0.64) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL30336996 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL14783716 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL9901085 | 0.82 | MAOB (0.54) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL15546230 | 0.81 | FFAR1 (0.52) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL25271189 | 0.81 | SOD1 (0.44) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL29590819 | 0.80 | WDR5 (0.62) | ALDH1A1LMNAKDM4ENR4A2MAOB | |
| SCHEMBL1308577 | 0.80 | WDR5 (0.62) | ALDH1A1LMNAKDM4ENR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444711-A1 | ANTIVIRAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023104882-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-06-15 | — | — | WO | disclosed |