SCHEMBL4362709

SCHEMBL4362709

O=C(Cl)COc1cccc(OCC(=O)Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.56
▸ KDM4E B2RXH2 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ ALOX15 P16050 1/20 0.48
▸ WDR5 P61964 1/20 0.46
▸ GRM4 Q14833 1/20 0.45
▸ PTPN7 P35236 1/20 0.44
▸ GAA P10253 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15063393 0.91 LMNA (0.53) LMNAKDM4EALDH1A1ALOX15GAA
SCHEMBL1308472 0.91 LMNA (0.72) LMNAKDM4EALDH1A1GAAKMT2A
SCHEMBL29590819 0.88 WDR5 (0.62) LMNAKDM4EALDH1A1WDR5GAA
SCHEMBL1308577 0.88 WDR5 (0.62) LMNAKDM4EALDH1A1WDR5GAA
SCHEMBL4362724 0.87 NR4A2 (0.46) LMNAGRM4KMT2AMEN1
SCHEMBL7941851 0.87 GRM4 (0.61) LMNAKDM4EALDH1A1GRM4GAA
SCHEMBL2719604 0.87 KMT2A (0.60) LMNAALDH1A1GAAKMT2AMEN1
SCHEMBL2718074 0.87 MEN1 (0.54) LMNAKDM4EALDH1A1KMT2AMEN1
SCHEMBL30457372 0.87 MEN1 (0.54) LMNAKDM4EALDH1A1KMT2AMEN1
SCHEMBL4361572 0.86 OGG1 (0.40) LMNAALDH1A1ALOX15PTPN7KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8602222-B2 Composite semipermeable membranes, methods for production thereof and uses thereof TORAY INDUSTRIES, INC. (JP) 2013-12-10 — — US claimed
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 — — US claimed
US-8602222-B2 Composite semipermeable membranes, methods for production thereof and uses thereof TORAY INDUSTRIES, INC. (JP) 2013-12-10 — — US disclosed
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 — — US disclosed
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 — — US disclosed
US-20090071903-A1 Composite Semipermeable Membranes, Methods for Production Thereof and Uses Thereof TORAY INDUSTRIES, INC. (JP) 2009-03-19 — — US disclosed
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