Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25305901 | 1.00 | NR4A2 (0.64) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL28106379 | 0.88 | MAPT (0.50) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL1612772 | 0.86 | LMNA (0.68) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL6714019 | 0.83 | RAB9A (0.77) | NR4A2LMNARAB9AMTNR1AMTNR1B | |
| SCHEMBL15636289 | 0.82 | NR4A2 (0.70) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL1612926 | 0.82 | NR4A2 (0.69) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL5067961 | 0.82 | ADAM17 (0.64) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL5434549 | 0.82 | NR4A2 (0.69) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL2085712 | 0.82 | NR4A2 (0.69) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL29647629 | 0.81 | ALDH1A1 (0.58) | LMNARAB9AMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444283-A1 | SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT | Tactogen Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107715-A1 | SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-06-15 | — | — | WO | disclosed |