Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | G6PD | P11413 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CCR6 | P51684 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939855 | 0.86 | NPSR1 (0.59) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL11563858 | 0.84 | PTGS1 (0.62) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL11668068 | 0.81 | PTGS2 (0.59) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL28343035 | 0.81 | PTGS1 (0.59) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL17661800 | 0.79 | PTGS1 (0.57) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL29615738 | 0.79 | PTGS1 (0.57) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL2345040 | 0.77 | MAPT (0.61) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL28343010 | 0.77 | PTGS1 (0.55) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL29567433 | 0.77 | PIM3 (0.64) | ALDH1A1MAPTNPSR1HPGDLMNA | |
| SCHEMBL3050771 | 0.77 | PIM3 (0.64) | ALDH1A1MAPTNPSR1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035799-A1 | METHOD FOR THE SYNTHESIS OF ANTHRACYCLINE-PEPTIDE CONJUGATES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2010-02-11 | — | — | US | disclosed |
| US-20050239688-A1 | Method for the synthesis of anthracycline-peptide conjugates | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2005-10-27 | — | — | US | disclosed |
| EP-1525002-A1 | METHOD FOR THE SYNTHESIS OF ANTHRACYCLINE-PEPTIDE CONJUGATES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004011033-A1 | METHOD FOR THE SYNTHESIS OF ANTHRACYCLINE-PEPTIDE CONJUGATES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2004-02-05 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035799-A1 | METHOD FOR THE SYNTHESIS OF ANTHRACYCLINE-PEPTIDE CONJUGATES | C9, DOHH, THOP1 | ALDH1A1 3168/4885MAPT 4454/4885NPSR1 1933/4885 |
| US-20050239688-A1 | Method for the synthesis of anthracycline-peptide conjugates | C9, DOHH, THOP1 | ALDH1A1 3168/4885MAPT 4454/4885NPSR1 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.