Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121206 | 0.94 | RORC (0.70) | RORCMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL27927815 | 0.82 | RORC (0.81) | RORCMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL119616 | 0.82 | L3MBTL1 (0.72) | RORCALDH1A1HTTMEN1KMT2A | |
| SCHEMBL119929 | 0.81 | RORC (0.79) | RORCMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL24279586 | 0.80 | MEN1 (0.60) | RORCALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10053472 | 0.79 | MAPT (0.60) | RORCMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL16557466 | 0.78 | KMT2A (0.67) | RORCMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL16557471 | 0.77 | SMN1; SMN2 (0.66) | RORCMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL29682641 | 0.76 | RORC (0.71) | RORCMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31650963 | 0.76 | ALDH1A1 (0.58) | MAPTPOLBALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023113461-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | 한국기초과학지원연구원 | 2023-06-22 | — | — | WO | claimed |
| WO-2023113461-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | 한국기초과학지원연구원 | 2023-06-22 | — | — | WO | disclosed |