Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27083693 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAESR2NR1H2 | |
| SCHEMBL27083701 | 0.79 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAESR2NR1H2 | |
| SCHEMBL1393643 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAESR2NR1H2 | |
| SCHEMBL18550027 | 0.76 | PRMT5 (0.51) | MAPK1GPR119 | |
| SCHEMBL30866165 | 0.76 | MAPT (0.57) | MAPTALDH1A1LMNAESR2NR1H2 | |
| SCHEMBL12987499 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAESR2MTOR | |
| SCHEMBL22169252 | 0.75 | ESR2 (0.48) | MAPTESR2NR1H2PIK3CAMTOR | |
| SCHEMBL30866131 | 0.74 | LMNA (0.57) | MAPTALDH1A1LMNAESR2NR1H2 | |
| SCHEMBL13779817 | 0.74 | NR1H2 (0.52) | MAPTESR2NR1H2PIK3CAMTOR | |
| SCHEMBL30995418 | 0.74 | HDAC1 (0.47) | MAPTLMNAESR2NR1H2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322683-A | Compounds as C5AR inhibitors | 科越医药(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |