Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764197 | 0.78 | PDE3B (0.39) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL22604308 | 0.77 | NCF1 (0.38) | KDM4EMAPK1 | |
| SCHEMBL22604304 | 0.77 | NCF1 (0.38) | KDM4EMAPK1 | |
| SCHEMBL22587373 | 0.76 | ESR1 (0.45) | — | |
| SCHEMBL27774508 | 0.76 | MAPT (0.43) | MAPT | |
| SCHEMBL27166286 | 0.75 | PPARG (0.39) | KDM4ERARBPARP10MAPT | |
| SCHEMBL22587389 | 0.75 | KDM4E (0.40) | KDM4EMAPK1MAPT | |
| SCHEMBL4204388 | 0.75 | APLNR (0.50) | MAPK1 | |
| SCHEMBL28172147 | 0.75 | KMO (0.40) | KDM4EMAPK1 | |
| SCHEMBL22604307 | 0.73 | CACNA1I (0.47) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825666-B | Dimeric or multimeric forms of mutant IDH inhibitors | 上海仕谱生物科技有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114127060-B | Dimeric or multimeric forms of mutant IDH inhibitors | 上海仕谱生物科技有限公司 | 2023-06-13 | — | — | CN | disclosed |