Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 11/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742362 | 1.00 | KMO (0.63) | KMOKMT2ASIRT2KDM4EGRM4 | |
| SCHEMBL30429075 | 0.85 | KMO (0.60) | KMOKMT2ASIRT2KDM4EPOLB | |
| SCHEMBL1940169 | 0.85 | KMO (0.60) | KMOKMT2ASIRT2KDM4EPOLB | |
| SCHEMBL30429175 | 0.84 | KMO (0.72) | KMOKMT2ASIRT2GRM4RAB9A | |
| SCHEMBL1939010 | 0.84 | KMO (0.72) | KMOKMT2ASIRT2GRM4RAB9A | |
| SCHEMBL1937820 | 0.82 | KMO (0.76) | KMOGRM4MAPTRAB9A | |
| SCHEMBL30459265 | 0.81 | KMO (0.79) | KMOKMT2AGRM4POLB | |
| SCHEMBL1938295 | 0.81 | KMO (0.79) | KMOKMT2AGRM4POLB | |
| SCHEMBL1938796 | 0.81 | KMO (0.75) | KMOGRM4 | |
| SCHEMBL30429642 | 0.81 | KMO (0.75) | KMOGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323583-A | Heterobiaryl compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-06-23 | — | — | CN | disclosed |