Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1327059 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL3738971 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL2068814 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL20457143 | 0.96 | L3MBTL1 (0.66) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL20457146 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL11606504 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL11606503 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL10805608 | 0.83 | L3MBTL1 (0.64) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL16489779 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL12786315 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121626-B | Macrolide compound, synthesis method, pharmaceutical composition and application thereof | 上海医药工业研究院有限公司 | 2023-06-16 | — | — | CN | disclosed |