Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489784 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 | |
| SCHEMBL12911265 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 | |
| SCHEMBL18810756 | 0.87 | L3MBTL1 (0.48) | L3MBTL1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL8977081 | 0.87 | L3MBTL1 (0.48) | L3MBTL1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL10805608 | 0.83 | L3MBTL1 (0.64) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 | |
| SCHEMBL1327059 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 | |
| SCHEMBL1204352 | 0.79 | L3MBTL1 (0.92) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 | |
| SCHEMBL2068814 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 | |
| SCHEMBL395524 | 0.79 | L3MBTL1 (0.92) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 | |
| SCHEMBL12786315 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227018-B1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | UNIV VIRGINIA COMMONWEALTH (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10000453-B2 | Chelation directed C—H activation reactions catalyzed by solid-supported palladium(II) catalysts | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-20170362181-A1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2017-12-21 | — | — | US | disclosed |
| US-9238667-B2 | Rhodium catalyst and method for producing amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| US-20150051416-A1 | RHODIUM CATALYST AND METHOD FOR PRODUCING AMINE COMPOUND | SPERA PHARMA, INC. (JP) | 2015-02-19 | — | — | US | disclosed |
| US-8481791-B2 | Homogeneous asymmetric hydrogenation process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| US-7902110-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20100168440-A1 | Homogeneous Asymmetric Hydrogenation Process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| US-7312347-B2 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-20070073065-A1 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | HDHD5, HHAT, HACL2 | L3MBTL1 2627/4885HPGD 138/4885G6PC1 3324/4885 |
| US-20170362181-A1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | WASF2, SCO2, SOD1 | L3MBTL1 1181/4885HPGD 1331/4885G6PC1 1926/4885 |
| US-10000453-B2 | Chelation directed C—H activation reactions catalyzed by solid-supported palladium(II) catalysts | WASF2, SOD1, CD274 | L3MBTL1 1229/4885HPGD 1319/4885G6PC1 1908/4885 |
| US-20070073065-A1 | Substituted optically active disphosphine compound | DHPS, DOHH, DHODH | L3MBTL1 4818/4885HPGD 548/4885G6PC1 1652/4885 |
| US-20100168440-A1 | Homogeneous Asymmetric Hydrogenation Process | HDHD5, HHAT, HVCN1 | L3MBTL1 2923/4885HPGD 167/4885G6PC1 3471/4885 |
| US-20150051416-A1 | RHODIUM CATALYST AND METHOD FOR PRODUCING AMINE COMPOUND | PRMT7, PRMT5, HNMT | L3MBTL1 4555/4885HPGD 1798/4885G6PC1 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.