Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1327059 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL2068814 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL30460772 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL20457143 | 0.96 | L3MBTL1 (0.66) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL20457146 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL11606504 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL11606503 | 0.87 | SMN1; SMN2 (0.51) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL10805608 | 0.83 | L3MBTL1 (0.64) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL16489779 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA | |
| SCHEMBL12786315 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HPGDG6PC1CYP2A6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280092-A1 | N-ACYLHYDRAZONE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | NEUROSEARCH A/S (DK) | 2010-11-04 | — | — | US | claimed |
| EP-3544973-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS | SUMITOMO CHEMICAL CO (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-10040772-B1 | Quinoxaline-fused dibenzosuberane based helicenes and organic electroluminescent device using the same | JUST ABOUT SHOWING CO., LTD. (TW) | 2018-08-07 | — | — | US | disclosed |
| US-10040772-B1 | Quinoxaline-fused dibenzosuberane based helicenes and organic electroluminescent device using the same | JUST ABOUT SHOWING CO., LTD. (TW) | 2018-08-07 | — | — | US | disclosed |
| EP-3216787-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-2502911-B1 | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20100280092-A1 | N-ACYLHYDRAZONE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | NEUROSEARCH A/S (DK) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280092-A1 | N-ACYLHYDRAZONE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | CHRNA3, CHRNA6, CHRNA2 | L3MBTL1 4093/4885HPGD 363/4885G6PC1 2797/4885 |
| US-10040772-B1 | Quinoxaline-fused dibenzosuberane based helicenes and organic electroluminescent device using the same | HRH4, HRH2, HRH3 | L3MBTL1 1743/4885HPGD 1040/4885G6PC1 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.