Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | XBP1 | P17861 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24584086 | 1.00 | KMT2A (0.53) | KMT2AHPGDMEN1TSHRNPSR1 | |
| SCHEMBL24584761 | 0.84 | NPC1 (0.63) | KMT2AHPGDMEN1TSHRNPSR1 | |
| SCHEMBL1126706 | 0.84 | ALDH1A1 (0.62) | KMT2AHPGDMEN1NPSR1NPC1 | |
| SCHEMBL22730880 | 0.79 | ALDH1A1 (0.56) | KMT2AHPGDMEN1TSHRNPSR1 | |
| SCHEMBL3341559 | 0.79 | ALDH1A1 (0.48) | KMT2AHPGDMEN1TSHRNPSR1 | |
| SCHEMBL24584793 | 0.79 | ALDH1A1 (0.56) | KMT2AHPGDMEN1NPSR1NPC1 | |
| SCHEMBL29697849 | 0.78 | FBP1 (0.51) | KMT2AHPGDMEN1ALDH1A1HTT | |
| SCHEMBL15151643 | 0.78 | HPGD (0.69) | KMT2AHPGDMEN1TSHRNPSR1 | |
| SCHEMBL28477674 | 0.77 | ADORA2B (0.58) | KMT2AHPGDMEN1TSHRNPSR1 | |
| SCHEMBL30532609 | 0.77 | NPC1 (0.57) | KMT2AHPGDMEN1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116675704-A | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114644634-B | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2023-06-20 | — | — | CN | disclosed |