Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | XBP1 | P17861 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24584793 | 0.93 | ALDH1A1 (0.56) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL29757646 | 0.92 | RAB9A (0.56) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL31567903 | 0.88 | LMNA (0.72) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL31567898 | 0.88 | LMNA (0.72) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL21480114 | 0.87 | CYP1A2 (0.58) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL95163 | 0.86 | ALDH1A1 (0.62) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL24584761 | 0.86 | NPC1 (0.63) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL1126748 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL31567904 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HTTNPSR1RXFP1NPC1 | |
| SCHEMBL31567905 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HTTNPSR1RXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497397-B2 | Pyrrole compounds useful as antifungals | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2025-12-16 | — | — | US | disclosed |
| EP-4071137-B1 | NOVEL PYRROLE COMPOUND | WIGEN BIOMEDICINE TECH SHANGHAI CO LTD (CN) | 2025-10-15 | — | — | EP | disclosed |
| US-20240327423-A1 | A SERIES OF PYRROLE DERIVATIVES AND THEIR PREPARATION METHOD AND THERAPEUTIC USE | Shenzhen Sungening Biological Co., Ltd (CN) | 2024-10-03 | — | — | US | disclosed |
| US-11819503-B2 | Method of treating coccidioides infection | F2G LTD (GB) | 2023-11-21 | — | — | US | disclosed |
| US-11819503-B2 | Method of treating coccidioides infection | F2G LTD (GB) | 2023-11-21 | — | — | US | disclosed |
| US-11819503-B2 | Method of treating coccidioides infection | F2G LTD (GB) | 2023-11-21 | — | — | US | disclosed |
| EP-4265621-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | Shenzhen Sungening Bio-Medical Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| CN-109982704-B | Pharmaceutical preparation | F2G有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-114206836-B | Novel pyrrole compounds | 微境生物医药科技(上海)有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116675704-A | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2023-09-01 | — | — | CN | disclosed |
| WO-2016079536-A1 | ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-08-27 | — | — | US | disclosed |
| US-8993574-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2015-03-31 | — | — | US | disclosed |
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2011-06-23 | — | — | US | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |
| WO-2003035614-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327423-A1 | A SERIES OF PYRROLE DERIVATIVES AND THEIR PREPARATION METHOD AND THERAPEUTIC USE | DHODH, PPOX, HPD | ALDH1A1 575/4885HTT 946/4885NPSR1 2703/4885 |
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | ALDH1A1 219/4885HTT 776/4885NPSR1 227/4885 |
| US-12497397-B2 | Pyrrole compounds useful as antifungals | PYCR1, CYP51A1, DPM1 | ALDH1A1 1752/4885HTT 2893/4885NPSR1 1160/4885 |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | ALDH1A1 219/4885HTT 776/4885NPSR1 227/4885 |
| US-11819503-B2 | Method of treating coccidioides infection | DPM1, OAT, OTC | ALDH1A1 415/4885HTT 4808/4885NPSR1 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.