Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849073 | 0.81 | KMT2A (0.42) | KMT2AALDH1A1P2RX3P2RX2LMNA | |
| SCHEMBL27409677 | 0.81 | KMT2A (0.42) | KMT2AALDH1A1P2RX3P2RX2LMNA | |
| SCHEMBL30462068 | 0.79 | CYP1A2 (0.49) | CYP17A1KMT2ACYP1A2CYP3A4HSD17B10 | |
| SCHEMBL30816550 | 0.76 | AURKA (0.38) | CYP17A1CYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL21174856 | 0.72 | MKNK1 (0.38) | CYP17A1 | |
| SCHEMBL30816580 | 0.71 | CYP17A1 (0.39) | CYP17A1CYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL30816598 | 0.71 | NNMT (0.45) | CYP17A1 | |
| SCHEMBL20640205 | 0.71 | TGFBR1 (0.39) | ALK | |
| SCHEMBL31521747 | 0.71 | CYP17A1 (0.39) | CYP17A1CYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL5735866 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741386-A1 | PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2026-05-13 | — | — | EP | disclosed |
| CN-118660872-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2024-09-17 | — | — | CN | disclosed |
| WO-2023208130-A1 | PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116496252-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |