Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816550 | 0.83 | AURKA (0.38) | CYP17A1NPC1EGFRHPGDCYP1A2 | |
| SCHEMBL16568952 | 0.76 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2ATMTP53 | |
| SCHEMBL2666364 | 0.74 | CYP2A6 (0.38) | NPC1SMN1; SMN2ATMCYP1A2CYP3A4 | |
| SCHEMBL30816626 | 0.73 | CYP17A1 (0.38) | CYP17A1EGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL31521747 | 0.72 | CYP17A1 (0.39) | CYP17A1SMN1; SMN2EGFRCYP1A2CYP3A4 | |
| SCHEMBL30462075 | 0.71 | CYP17A1 (0.40) | CYP17A1CYP1A2CYP3A4TDP1HSD17B10 | |
| SCHEMBL30538048 | 0.71 | CYP17A1 (0.38) | CYP17A1EGFRCYP1A2CYP3A4TDP1 | |
| SCHEMBL30816561 | 0.70 | ALDH1A1 (0.44) | CYP17A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL31521754 | 0.69 | GAA (0.42) | CYP17A1NPC1RAB9ASMN1; SMN2ATM | |
| SCHEMBL30462068 | 0.69 | CYP1A2 (0.49) | CYP17A1SMN1; SMN2HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092779-A1 | USP1 INHIBITORS AND USES THEREOF | ZENTAUR THERAPEUTICS USA INC. | 2024-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092779-A1 | USP1 INHIBITORS AND USES THEREOF | USP1, USP28, USP2 | CYP17A1 1682/4885NPC1 1482/4885RAB9A 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.