SCHEMBL3046274

SCHEMBL3046274

O=C(COc1ccc2ccccc2c1)OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.68
KDM4E B2RXH2 1/20 0.68
LMNA P02545 1/20 0.68
PTPN7 P35236 1/20 0.64
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
PPARG P37231 3/20 0.63
NCOA2 Q15596 3/20 0.63
NCOA1 Q15788 3/20 0.63
NCOA3 Q9Y6Q9 3/20 0.63
ALOX5 P09917 1/20 0.63
MRGPRX4 Q96LA9 1/20 0.56
ALDH1A1 P00352 2/20 0.55
GPR183 P32249 1/20 0.54
HTT P42858 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
NR2E3 Q9Y5X4 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8681578 0.84 ALDH1A1 (0.61) POLBKDM4ELMNAKMT2AALDH1A1
SCHEMBL8013977 0.83 ALOX15 (0.61) POLBKDM4ELMNAPTPN7MEN1
SCHEMBL8011529 0.83 LMNA (0.62) POLBKDM4ELMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL27505257 0.82 ALDH1A1 (0.59) POLBKDM4ELMNAKMT2AALDH1A1
SCHEMBL9770330 0.82 PTPN7 (0.64) POLBKDM4EPTPN7MEN1KMT2A
SCHEMBL24115517 0.81 PPARG (0.50) POLBKDM4ELMNAPTPN7MEN1
SCHEMBL5288304 0.81 MAPT (0.59) POLBKDM4ELMNAPPARGALDH1A1
SCHEMBL27370553 0.81 PTPN7 (0.63) POLBKDM4EPTPN7MEN1KMT2A
SCHEMBL5285624 0.81 MRGPRX4 (0.58) POLBKDM4ELMNAMRGPRX4ALDH1A1
SCHEMBL14405820 0.80 GAA (0.59) POLBKDM4ELMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8647878-B2 Highly refractive immersion liquids and their use CARL ZEISS AG (DE) 2014-02-11 US disclosed
US-8647878-B2 Highly refractive immersion liquids and their use CARL ZEISS AG (DE) 2014-02-11 US disclosed
US-8647878-B2 Highly refractive immersion liquids and their use CARL ZEISS AG (DE) 2014-02-11 US disclosed
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use CARL ZEISS AG (DE) 2010-08-26 US disclosed
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use CARL ZEISS AG (DE) 2010-08-26 US disclosed
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use CARL ZEISS AG (DE) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100212547-A1 Highly Refractive Immersion Liquids And Their Use NR4A3, NR2E3, NR4A1 POLB 3554/4885KDM4E 3365/4885LMNA 2361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.