Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5288304 | 0.86 | MAPT (0.59) | KDM4ELMNAPOLBKDM5ACASP1 | |
| SCHEMBL8681578 | 0.86 | ALDH1A1 (0.61) | KDM4ELMNAPOLBNR4A2KDM5A | |
| Hydrochloric Acid SCHEMBL27505257 | 0.84 | ALDH1A1 (0.59) | KDM4ELMNAPOLBNR4A2KDM5A | |
| SCHEMBL26641488 | 0.84 | MAOB (0.65) | MRGPRX4KDM4ELMNAPOLBNR4A2 | |
| SCHEMBL22214976 | 0.84 | NR4A2 (0.73) | MRGPRX4KDM4ELMNAPOLBNR4A2 | |
| SCHEMBL6159651 | 0.84 | MAOB (0.65) | KDM4ELMNAPOLBNR4A2KDM5A | |
| SCHEMBL13141347 | 0.82 | PPARA (0.53) | KDM4ELMNAPOLBNR4A2KDM5A | |
| SCHEMBL29460406 | 0.82 | MAOA (0.69) | KDM4ELMNAPOLBNR4A2ALDH1A1 | |
| SCHEMBL22214975 | 0.82 | MAOA (0.69) | KDM4ELMNAPOLBNR4A2ALDH1A1 | |
| SCHEMBL3046274 | 0.81 | POLB (0.68) | MRGPRX4KDM4ELMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | MRGPRX4 1039/4885KDM4E 4305/4885LMNA 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.