Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210508 | 0.81 | IDO1 (0.53) | IDO1SCN2ANPC1RAB9AKMO | |
| SCHEMBL29795310 | 0.78 | GRIN1 (0.38) | IDO1SCN2ANPC1RAB9AALDH1A1 | |
| SCHEMBL27168511 | 0.74 | KIF11 (0.58) | CLK4GRM5ALDH1A1TSHRSLC6A7 | |
| SCHEMBL29539055 | 0.72 | RAB9A (0.46) | CYP2A6NPC1RAB9ACLK4DYRK1A | |
| SCHEMBL30788615 | 0.68 | KIF11 (0.50) | NPC1RAB9ACLK4ALDH1A1SLC6A7 | |
| SCHEMBL28461127 | 0.67 | IDO1 (0.50) | IDO1SCN2ANPC1RAB9AKMO | |
| SCHEMBL30658161 | 0.66 | TSHR (0.44) | IDO1ALDH1A1TSHRKIF11NPY5R | |
| SCHEMBL29979429 | 0.66 | TGFBR1 (0.60) | IDO1SCN2ANPC1RAB9AKMO | |
| SCHEMBL4025464 | 0.66 | TGFBR1 (0.60) | IDO1SCN2ANPC1RAB9AKMO | |
| SCHEMBL14357355 | 0.65 | KIF11 (0.61) | CYP2A6CLK4DYRK1AALDH1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605408-B | 5-hydroxy-1, 3-disubstituted phenylpyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2023-06-16 | — | — | CN | disclosed |