Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025464 | 1.00 | TGFBR1 (0.60) | TGFBR1CTSSIDO1KMOGRM5 | |
| SCHEMBL4033214 | 0.98 | TGFBR1 (0.59) | TGFBR1CTSSIDO1KMOGRM5 | |
| SCHEMBL13878868 | 0.85 | MAPK1 (0.52) | TGFBR1GRM5L3MBTL1LMNACBFB | |
| SCHEMBL30090584 | 0.85 | NPC1 (0.52) | TGFBR1GRM5KDM1AL3MBTL1LMNA | |
| SCHEMBL4577045 | 0.85 | NPC1 (0.52) | TGFBR1GRM5KDM1AL3MBTL1LMNA | |
| SCHEMBL14073533 | 0.85 | TRPV1 (0.53) | TGFBR1GRM5CBFBSMN1; SMN2TRPV1 | |
| SCHEMBL4404606 | 0.82 | KIF11 (0.56) | TGFBR1CTSSGRM5ALDH1A1L3MBTL1 | |
| SCHEMBL30153625 | 0.82 | KIF11 (0.56) | TGFBR1CTSSGRM5ALDH1A1L3MBTL1 | |
| SCHEMBL9874816 | 0.81 | CTSK (0.51) | TGFBR1CTSSIDO1KMOGRM5 | |
| SCHEMBL502867 | 0.80 | KDM4E (0.62) | GRM5ALDH1A1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160354-A | Method for efficiently synthesizing aryl silicon compound | 南阳师范学院 | 2022-10-11 | — | — | CN | claimed |
| EP-4540258-A1 | CATALYST | The University of Manchester (GB) | 2025-04-23 | — | — | EP | disclosed |
| CN-117430549-A | Method for preparing isonicotinic acid compound by taking carbon dioxide as carboxyl source | 南开大学 | 2024-01-23 | — | — | CN | disclosed |
| WO-2023247563-A1 | CATALYST | THE UNIVERSITY OF MANCHESTER (GB) | 2023-12-28 | — | — | WO | disclosed |
| CN-115160354-A | Method for efficiently synthesizing aryl silicon compound | 南阳师范学院 | 2022-10-11 | — | — | CN | disclosed |