SCHEMBL30463403

NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	5/20	0.59

▸	OPRD1	P41143	4/20	0.59

▸	NTSR1	P30989	6/20	0.51

▸	NTSR2	O95665	5/20	0.51

▸	SORT1	Q99523	3/20	0.51

▸	SLC6A2	P23975	1/20	0.51

▸	F2	P00734	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30463401	0.99	OPRM1 (0.59)	OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL30631183	0.94	OPRD1 (0.60)	OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL30287598	0.92	OPRD1 (0.62)	OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL30629451	0.90	OPRD1 (0.59)	OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL30116347	0.90	OPRD1 (0.57)	OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL30116348	0.90	OPRD1 (0.57)	OPRM1OPRD1
SCHEMBL30439569	0.90	OPRD1 (0.57)	OPRM1OPRD1
SCHEMBL30439763	0.89	OPRD1 (0.56)	OPRM1OPRD1
SCHEMBL30116351	0.89	OPRD1 (0.65)	OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL30503059	0.88	OPRD1 (0.56)	OPRM1OPRD1NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116209475-A	Therapeutic uses comprising a triple agonist long-acting conjugate or a combination of triple agonists	韩美药品株式会社	2023-06-02	—	—	CN	disclosed